056 Randy Seeley, PhD: The Biology of Body Weight

by reeger on July 17, 2015


056 Randy Seeley, PhD

In this episode I bring back Randy Seeley, Ph.D.. Dr Seeley is a research scientist at the University of Michigan School of Medicine. The focus of Dr Seeley’s work is examining how various hormones produced by the body work to influence the brain, food intake, and body weight. Dr Seeley and I last spoke one year ago in episode 34, titled Set-Point, Biology, Environment, & Obesity. This was a very popular episode. So popular, I decided to ask Dr Seeley back to review some of the important concepts that we discussed last year and to take the conversation further.

Discussed in this episode:

  • Who Dr Seeley studies and why
  • The principles of how hormones fit into the role of food intake and body
  • How our scientific understanding of hormonal regulation is evolving and changing
  • Our body weight is regulated over time, separate from our conscious desire for our weight
  • The hormone called Leptin and its complicated role in helping control food intake
  • How the body is similar to a home’s heating system, and not similar
  • Why WHAT we eat matters to the hormonal signals that communicate with our brain saying whether we are hungry or satisfied
  • What is Leptin resistance
  • How our genetics influences our weight
  • What the term “obesogenic” means
  • The important role of gut hormones that communicate with the brain
  • What happens to our hormones when we go on a diet
  • How the environment influences feelings of hunger
  • Is there a non-surgical equivalent to losing weight and maintain that weight off
  • Why does hunger go away after bariatric surgery
  • Why does hunger come back after bariatric surgery
  • Does bariatric surgery work through restriction or something else
  • The hormonal differences between gastric banding, sleeve gastrectomy, and roux-en-Y gastric bypass
  • Does the body care about weight level or fat level
  • Why do people eventually stop losing weight after bariatric surgery
  • What if you do not lose as much weight as you hoped with bariatric surgery
  • The future of pre-bariatric surgery work-up may include genetic testing
  • Dr Seeley will be presenting at the Obesity Action Coalition’s Your Weight Matters Convention in San Antonio, Tx. The title of his talk will be: Think on this: Understanding the Brain’s Role in Weight and Your Behaviors

Don’t be shy! Connect with me!
Weight Loss Surgery Podcast Facebook
Southern Oregon Bariatric Center Facebook
Twitter @preegerc

I believe in you,


{ 4 comments… read them below or add one }

Liz Kelly August 18, 2015 at 5:32 am

Hi Reeger,
I was so excited to see a link to this podcast posted by APound of Cure on Facebook today. Congratulations and thank you for all you do to make this happen .
Fondly, Liz


reeger August 20, 2015 at 1:31 am

Hi Liz,
I did not know the podcast got promoted. Can you share the link for what you say? Thanks! Reeger


Julie T April 6, 2016 at 6:18 pm

Is there a written transcript of this podcast available?


reeger April 17, 2016 at 8:17 pm

Hi Julie, I am sorry these is not a written transcript of this episode. That is a great idea but at this time since I am 100% self produced it is enough to get each episode out : ) However, I promise if I ever do get this and any other episode out in any other form besides an audio podcast I will let you know. Reeger


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